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Microskin‐Inspired Injectable MSC‐Laden Hydrogels for Scarless Wound Healing with Hair Follicles

封面设计 | First Published: 2020-05-21

Xin Zheng Zhaozhao Ding Weinan Cheng Qiang Lu Xiangdong Kong Xiaozhong Zhou Guozhong Lu David L. Kaplan

In article number 2000041 by Qiang Lu, Xiaozhong Zhou, Guozhong Lu, and co‐workers, microgels composed of aligned silk nanofibers are used to load mesenchymal stem cells (MSCs) to actively modulate the paracrine. The MSCs‐laden microgels are blended with injectable silk nanofiber hydrogels to accelerate the wound healing. The synergistic action of MSCs‐laden hydrogel systems stimulates angiogenesis and M1‐M2 phenotype switching of macrophages, achieving scarless skin regeneration with hair follicles.

原文链接

https://onlinelibrary.wiley.com/doi/10.1002/adhm.202070029

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