hide

首页 / 新闻

Sublethal Levels of Antibiotics Promote Bacterial Persistence in Epithelial Cells

封面设计 | First Published: 2020-09-23

Xiaoye Liu Fei Liu Shuangyang Ding Jianzhong Shen Kui Zhu

In article number 1900840, Jianzhong Shen, Kui Zhu, and co‐workers present how many extracellular bacteria can invade and survive in epithelial cells in both in vivo and in vitro models. Once such bacteria survive in host cells, they act as “Trojan horses” to tolerate various stresses including antibiotic therapy. Such adaption endows bacteria with common tolerance to multiple antibiotics. Sublethal levels of antibiotics not only promote the production of bacterial toxins to increase bacterial invasion, but also cause mitochondrial dysfunction and retard the clearance of internalized bacteria.

原文链接

https://onlinelibrary.wiley.com/doi/10.1002/advs.202070104

回到顶部

联系我们

  • 地址

    辽宁省沈阳市铁西区北一西路52甲号830-06

  • 热线电话

    13236639606 或 13022406957

  • QQ

    客服1:1114371869 客服2:2501950479 客服3:1114371777

官方分享

辽公网安备21010602000232号 ICP证:辽ICP备16001548号-2

copyright © 2016 沈阳智研科技有限公司 版权所有网站建

沈阳网站建设:龙兴科技