Earth‐abundant/biocompatible metal catalysts for the asymmetric cis‐dihydroxylation (AD) of trisubstituted alkenes, in which OsO4‐based catalysts have been widely used, are highly appealing. In their Research Article on page 16561, C.‐M. Che and co‐workers describe a cis‐FeII(chiral N4 ligand)/H2O2 method that is an alternative/complement to the OsO4‐based method and converts various trisubstituted alkenes into cis‐diols in synthetically useful yields with excellent enantioselectivity under mild conditions.

原文链接

https://onlinelibrary.wiley.com/doi/10.1002/anie.202010075