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Antibiotic Resistance: Photo‐Disassembly of Membrane Microdomains Revives Conventional Antibiotics against MRSA

Jie Hui Pu‐Ting Dong Lijia Liang Taraknath Mandal Junjie Li Erlinda R. Ulloa Yuewei Zhan Sebastian Jusuf Cheng Zong Mohamed N. Seleem George Y. Liu Qiang Cui Ji‐Xin Cheng

封面设计 | First Published: 2020-03-23

In article number 1903117, Ji‐Xin Cheng and co‐workers report an endogenous chromophore‐based phototherapy platform to combat antibiotic‐resistance Staphylococcus aureus infections. Functional membrane microdomains of Staphylococcus aureus are catastrophically disrupted via photochemical decomposition of membrane‐bound carotenoid pigment, staphyloxanthin, thus reviving a broad spectrum of conventional antibiotics against Staphylococcus aureus.

原文链接

https://onlinelibrary.wiley.com/doi/10.1002/advs.202070035

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