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Gene‐Hydrogel Microenvironments: Gene‐Hydrogel Microenvironment Regulates Extracellular Matrix Metabolism Balance in Nucleus Pulposus

论文插图 封面设计 | First Published: 2020-01-09

Wei Chen Hao Chen Dandan Zheng Hongbo Zhang Lianfu Deng Wenguo Cui Yuhui Zhang Hélder A. Santos Hongxing Shen

In degenerative diseases, microenvironment deterioration is often followed by a vicious circle of cell death and aggravation of microenvironment deterioration. To break the cycle, a gene‐hydrogel microenvironment is constructed in article number 1902099 by Yuhui Zhang, Hélder A. Santos, Hongxing Shen, and co‐workers in situ, which regulates the synthesis/catabolism balance of extracellular matrix in the nucleus pulposus of the intervertebral disc and improves the tissue microenvironment regeneration.

原文链接

https://onlinelibrary.wiley.com/doi/10.1002/advs.202070001

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