Black phosphorus quantum dots (BPQDs) were successfully synthesized by using a pulsed laser ablation (PLA) method. A strong, stable, excitation‐independent photoluminescence (PL) emission of BPQDs in the violet–blue wavelength region was clearly observed, and the quantum yield of the as‐prepared sample was 20.7%, which is three times higher than that of the BPQDs prepared by probe ultrasonic exfoliation (approximately 7.2%). In addition, BPQDs are also utilized in bioimaging in HeLa cells (image background), showing an intense and stable PL signal and excellent biocompatibility. Hence, this work indicates that the obtained BPQDs with high quantum yield and stable PL emission have great potential for biomedical applications, including biolabeling, bioimaging, and drug delivery. More information can be found in the Full Paper by Xiaoling Zhang et al. on page 1842 in Issue 14, 2018 (DOI: 10.1002/asia.201800482).